Pathology tissue–chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples

Epigenetic alterations in the pattern of DNA and histone modifications play a crucial role in cancer development. Analysis of patient samples, however, is hampered by technical limitations in the study of chromatin structure from pathology archives that usually consist of heavily fixed, paraffin-emb...

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Detalhes bibliográficos
Main Authors: Fanelli, Mirco, Amatori, Stefano, Barozzi, Iros, Soncini, Matias, Dal Zuffo, Roberto, Bucci, Gabriele, Capra, Maria, Quarto, Micaela, Dellino, Gaetano Ivan, Mercurio, Ciro, Alcalay, Myriam, Viale, Giuseppe, Pelicci, Pier Giuseppe, Minucci, Saverio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003125/
https://ncbi.nlm.nih.gov/pubmed/21106756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007647107
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