Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with l-dopa–induced dyskinesia

l-dopa–induced dyskinesia (LID) is a common debilitating complication of dopamine replacement therapy in Parkinson's disease. Recent evidence suggests that LID may be linked causally to a hyperactivation of the Ras–ERK signaling cascade in the basal ganglia. We set out to determine whether spec...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Fasano, Stefania, Bezard, Erwan, D'Antoni, Angela, Francardo, Veronica, Indrigo, Marzia, Qin, Li, Doveró, Sandra, Cerovic, Milica, Cenci, M. Angela, Brambilla, Riccardo
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003069/
https://ncbi.nlm.nih.gov/pubmed/21115823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012071107
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker