Nociceptin/Orphanin FQ Receptor Agonists Attenuate l-DOPA-Induced Dyskinesias

In the present study we investigated whether the neuropeptide nociceptin/orphanin FQ (N/OFQ), previously implicated in the pathogenesis of Parkinson's disease, also affects l-DOPA-induced dyskinesia. In striatal slices of naive rodents, N/OFQ (0.1–1 μm) prevented the increase of ERK phosphoryla...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Marti, Matteo, Rodi, Donata, Li, Qin, Guerrini, Remo, Fasano, Stefania, Morella, Ilaria, Tozzi, Alessandro, Brambilla, Riccardo, Calabresi, Paolo, Simonato, Michele, Bezard, Erwan, Morari, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794016/
https://ncbi.nlm.nih.gov/pubmed/23152595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6408-11.2012
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