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Dichotomy between factors inducing the immunosuppressive enzyme IL-4-induced gene 1 (IL4I1) in B lymphocytes and mononuclear phagocytes

Macrophages (Mϕ) and dendritic cells (DC) are key cells controlling tissue homeostasis and response to aggressions. In this work, we demonstrate that Mϕ and DC are the major producers of the phenylalanine catabolizing enzyme IL4I1 under inflammatory conditions. IL4I1 was first described in B cells,...

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Detalhes bibliográficos
Main Authors: Marquet, Jeanine, Lasoudris, Fanette, Cousin, Céline, Puiffe, Marie-Line, Martin-Garcia, Nadine, Baud, Véronique, Chereau, Fanny, Farcet, Jean-Pierre, Molinier-Frenkel, Valérie, Castellano, Flavia
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley-VCH 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001484/
https://ncbi.nlm.nih.gov/pubmed/20683900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040428
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