Dichotomy between factors inducing the immunosuppressive enzyme IL-4-induced gene 1 (IL4I1) in B lymphocytes and mononuclear phagocytes

Macrophages (Mϕ) and dendritic cells (DC) are key cells controlling tissue homeostasis and response to aggressions. In this work, we demonstrate that Mϕ and DC are the major producers of the phenylalanine catabolizing enzyme IL4I1 under inflammatory conditions. IL4I1 was first described in B cells,...

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Autors principals: Marquet, Jeanine, Lasoudris, Fanette, Cousin, Céline, Puiffe, Marie-Line, Martin-Garcia, Nadine, Baud, Véronique, Chereau, Fanny, Farcet, Jean-Pierre, Molinier-Frenkel, Valérie, Castellano, Flavia
Format: Artigo
Idioma:Inglês
Publicat: Wiley-VCH 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001484/
https://ncbi.nlm.nih.gov/pubmed/20683900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040428
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