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The IL4I1 Enzyme: A New Player in the Immunosuppressive Tumor Microenvironment

The high metabolic needs of T lymphocytes in response to activation make them particularly vulnerable to modifications of their biochemical milieu. Immunosuppressive enzymes produced in the tumor microenvironment modify nutrient availability by catabolizing essential or semi-essential amino acids an...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Molinier-Frenkel, Valérie, Prévost-Blondel, Armelle, Castellano, Flavia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678094/
https://ncbi.nlm.nih.gov/pubmed/31330829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8070757
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