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Intrinsically disordered PEP-19 confers unique dynamic properties to apo and calcium calmodulin
PEP-19 (Purkinje cell protein 4) is an intrinsically disordered protein with an IQ calmodulin (CaM) binding motif. Expression of PEP-19 was recently shown to protect cells from apoptosis and cell death due to Ca(2+) overload. Our initial studies showed that PEP-19 causes novel and dramatic increases...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3001392/ https://ncbi.nlm.nih.gov/pubmed/20973509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100500m |
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