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Neurogranin Alters the Structure and Calcium Binding Properties of Calmodulin
Neurogranin (Ng) is a member of the IQ motif class of calmodulin (CaM)-binding proteins, and interactions with CaM are its only known biological function. In this report we demonstrate that the binding affinity of Ng for CaM is weakened by Ca(2+) but to a lesser extent (2–3-fold) than that previousl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4031520/ https://ncbi.nlm.nih.gov/pubmed/24713697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.560656 |
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