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Dissecting cooperative calmodulin binding to CaM kinase II: a detailed stochastic model
Calmodulin (CaM) is a major Ca(2+) binding protein involved in two opposing processes of synaptic plasticity of CA1 pyramidal neurons: long-term potentiation (LTP) and depression (LTD). The N- and C-terminal lobes of CaM bind to its target separately but cooperatively and introduce complex dynamics...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3617043/ https://ncbi.nlm.nih.gov/pubmed/19609660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10827-009-0173-3 |
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