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Dissecting cooperative calmodulin binding to CaM kinase II: a detailed stochastic model

Calmodulin (CaM) is a major Ca(2+) binding protein involved in two opposing processes of synaptic plasticity of CA1 pyramidal neurons: long-term potentiation (LTP) and depression (LTD). The N- and C-terminal lobes of CaM bind to its target separately but cooperatively and introduce complex dynamics...

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Hlavní autoři: Byrne, Michael J., Putkey, John A., Waxham, M. Neal, Kubota, Yoshihisa
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617043/
https://ncbi.nlm.nih.gov/pubmed/19609660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10827-009-0173-3
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