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Neurogranin Controls the Spatiotemporal Pattern of Postsynaptic Ca(2+)/CaM Signaling

Neurogranin (Ng) is a postsynaptic IQ-motif containing protein that accelerates Ca(2+) dissociation from calmodulin (CaM), a key regulator of long-term potentiation and long-term depression in CA1 pyramidal neurons. The exact physiological role of Ng, however, remains controversial. Two genetic knoc...

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Detalhes bibliográficos
Main Authors: Kubota, Yoshihisa, Putkey, John A., Waxham, M. Neal
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084249/
https://ncbi.nlm.nih.gov/pubmed/17704141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.106849
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