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The Calmodulin Regulator Protein, PEP-19, Sensitizes ATP-induced Ca(2+) Release
PEP-19 is a small, intrinsically disordered protein that binds to the C-domain of calmodulin (CaM) via an IQ motif and tunes its Ca(2+) binding properties via an acidic sequence. We show here that the acidic sequence of PEP-19 has intrinsic Ca(2+) binding activity, which may modulate Ca(2+) binding...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3548510/ https://ncbi.nlm.nih.gov/pubmed/23204517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.411314 |
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