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CpG Oligodeoxynucleotides Stimulate Protective Innate Immunity against Pulmonary Klebsiella Infection

Bacterial pneumonia is a leading cause of mortality in the United States. Innate immune responses, including type-1 cytokine production, are critical to the effective clearance of bacterial pathogens from the lung. Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG dinucleotide motifs...

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Detalhes bibliográficos
Main Authors: Deng, Jane C., Moore, Thomas A., Newstead, Michael W., Zeng, Xianying, Krieg, Arthur M., Standiford, Theodore J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001228/
https://ncbi.nlm.nih.gov/pubmed/15470059
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