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STAT4 Is a Critical Mediator of Early Innate Immune Responses against Pulmonary Klebsiella Infection

Bacterial pneumonia is a leading cause of morbidity and mortality in the U.S. An effective innate immune response is critical for the clearance of bacteria from the lungs. IL-12, a key T1 cytokine in innate immunity, signals through STAT4. Thus, understanding how STAT4 mediates pulmonary immune resp...

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Bibliografiske detaljer
Main Authors: Deng, Jane C., Zeng, Xianying, Newstead, Michael, Moore, Thomas A., Tsai, Wan C., Thannickal, Victor J., Standiford, Theodore J.
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001230/
https://ncbi.nlm.nih.gov/pubmed/15356157
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