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Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival

Tec family kinases have important roles in lymphocytes, however little is known about their function in monocytes/macrophages. Here we report that Tec family kinases are essential for macrophage colony stimulating factor (M-CSF)-induced signaling pathways that regulate macrophage survival. Compared...

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Bibliographische Detailangaben
Hauptverfasser: Melcher, Martin, Unger, Bernd, Schmidt, Uwe, Rajantie, Iiro A, Alitalo, Kari, Ellmeier, Wilfried
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001193/
https://ncbi.nlm.nih.gov/pubmed/18523268
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