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The Tyrosine Kinase Btk Regulates the Macrophage Response to Listeria monocytogenes Infection

In this study we investigated the role of Bruton's tyrosine kinase (Btk) in the immune response to the Gram-positive intracellular bacterium Listeria monocytogenes (Lm). In response to Lm infection, Btk was activated in bone marrow-derived macrophages (BMMs) and Btk (−/−) BMMs showed enhanced T...

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Autors principals: Köprülü, Afitap Derya, Kastner, Renate, Wienerroither, Sebastian, Lassnig, Caroline, Putz, Eva Maria, Majer, Olivia, Reutterer, Benjamin, Sexl, Veronika, Kuchler, Karl, Müller, Mathias, Decker, Thomas, Ellmeier, Wilfried
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609758/
https://ncbi.nlm.nih.gov/pubmed/23544144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060476
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