The Tyrosine Kinase Btk Regulates the Macrophage Response to Listeria monocytogenes Infection

In this study we investigated the role of Bruton's tyrosine kinase (Btk) in the immune response to the Gram-positive intracellular bacterium Listeria monocytogenes (Lm). In response to Lm infection, Btk was activated in bone marrow-derived macrophages (BMMs) and Btk (−/−) BMMs showed enhanced T...

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Detalhes bibliográficos
Main Authors: Köprülü, Afitap Derya, Kastner, Renate, Wienerroither, Sebastian, Lassnig, Caroline, Putz, Eva Maria, Majer, Olivia, Reutterer, Benjamin, Sexl, Veronika, Kuchler, Karl, Müller, Mathias, Decker, Thomas, Ellmeier, Wilfried
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609758/
https://ncbi.nlm.nih.gov/pubmed/23544144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060476
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