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O(6)-Methylguanine induces altered proteins at the level of transcription in human cells

O(6)-Methylguanine (O(6)-meG), which is produced in DNA following exposure to methylating agents, instructs human RNA polymerase II to mis-insert bases opposite the lesion during transcription. In this study, we examined the effect of O(6)-meG on transcription in human cells and investigated the sub...

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Detalhes bibliográficos
Main Authors: Burns, John A., Dreij, Kristian, Cartularo, Laura, Scicchitano, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001077/
https://ncbi.nlm.nih.gov/pubmed/20702424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq706
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