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Deep sequencing analysis of mutations resulting from the incorporation of dNTP analogs

Next-generation DNA sequencing technology was used to score >100 000 mutations resulting from exposure of a nucleic acid template to a mutagenic dNTP analog during a single pass of a DNA polymerase. An RNA template of known secondary structure was reverse transcribed in the presence of 8-oxo-dGTP...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Petrie, Katherine L., Joyce, Gerald F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001061/
https://ncbi.nlm.nih.gov/pubmed/20693528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq685
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