Sphingolipid-mediated Inhibition of Apoptotic Cell Clearance by Alveolar Macrophages

A decreased clearance of apoptotic cells (efferocytosis) by alveolar macrophages (AM) may contribute to inflammation in emphysema. The up-regulation of ceramides in response to cigarette smoking (CS) has been linked to AM accumulation and increased detection of apoptotic alveolar epithelial and endo...

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Hlavní autoři: Petrusca, Daniela N., Gu, Yuan, Adamowicz, Jeremy J., Rush, Natalia I., Hubbard, Walter C., Smith, Patricia A., Berdyshev, Evgeni V., Birukov, Konstantin G., Lee, Chao-Hung, Tuder, Rubin M., Twigg, Homer L., Vandivier, R. William, Petrache, Irina
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001012/
https://ncbi.nlm.nih.gov/pubmed/20956540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.137604
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