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Apoptotic Sphingolipid Signaling by Ceramides in Lung Endothelial Cells

The de novo pathway of ceramide synthesis has been implicated in the pathogenesis of excessive lung apoptosis and murine emphysema. Intracellular and paracellular-generated ceramides may trigger apoptosis and propagate the death signals to neighboring cells, respectively. In this study we compared t...

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Библиографические подробности
Главные авторы: Medler, Terry R., Petrusca, Daniela N., Lee, Patty J., Hubbard, Walter C., Berdyshev, Evgeny V., Skirball, Jarrett, Kamocki, Krzysztof, Schuchman, Edward, Tuder, Rubin M., Petrache, Irina
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396244/
https://ncbi.nlm.nih.gov/pubmed/18192502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0274OC
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