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Apoptotic Sphingolipid Signaling by Ceramides in Lung Endothelial Cells

The de novo pathway of ceramide synthesis has been implicated in the pathogenesis of excessive lung apoptosis and murine emphysema. Intracellular and paracellular-generated ceramides may trigger apoptosis and propagate the death signals to neighboring cells, respectively. In this study we compared t...

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Detalhes bibliográficos
Main Authors: Medler, Terry R., Petrusca, Daniela N., Lee, Patty J., Hubbard, Walter C., Berdyshev, Evgeny V., Skirball, Jarrett, Kamocki, Krzysztof, Schuchman, Edward, Tuder, Rubin M., Petrache, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396244/
https://ncbi.nlm.nih.gov/pubmed/18192502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0274OC
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