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Apoptotic Sphingolipid Signaling by Ceramides in Lung Endothelial Cells

The de novo pathway of ceramide synthesis has been implicated in the pathogenesis of excessive lung apoptosis and murine emphysema. Intracellular and paracellular-generated ceramides may trigger apoptosis and propagate the death signals to neighboring cells, respectively. In this study we compared t...

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Autori principali: Medler, Terry R., Petrusca, Daniela N., Lee, Patty J., Hubbard, Walter C., Berdyshev, Evgeny V., Skirball, Jarrett, Kamocki, Krzysztof, Schuchman, Edward, Tuder, Rubin M., Petrache, Irina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396244/
https://ncbi.nlm.nih.gov/pubmed/18192502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0274OC
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