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Abl Kinases Are Required for Invadopodia Formation and Chemokine-induced Invasion

The Abl tyrosine kinases, Abl and Arg, play a role in the regulation of the actin cytoskeleton by modulating cell-cell adhesion and cell motility. Deregulation of both the actin cytoskeleton and Abl kinases have been implicated in cancers. Abl kinase activity is elevated in a number of metastatic ca...

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Hlavní autoři: Smith-Pearson, Pameeka S., Greuber, Emileigh K., Yogalingam, Gouri, Pendergast, Ann Marie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001002/
https://ncbi.nlm.nih.gov/pubmed/20937825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.147330
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