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Abl Kinases Are Required for Invadopodia Formation and Chemokine-induced Invasion
The Abl tyrosine kinases, Abl and Arg, play a role in the regulation of the actin cytoskeleton by modulating cell-cell adhesion and cell motility. Deregulation of both the actin cytoskeleton and Abl kinases have been implicated in cancers. Abl kinase activity is elevated in a number of metastatic ca...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3001002/ https://ncbi.nlm.nih.gov/pubmed/20937825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.147330 |
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