Abl Kinases Regulate Autophagy by Promoting the Trafficking and Function of Lysosomal Components

Autophagy is a lysosome-dependent degradative pathway that regulates the turnover of intracellular organelles, parasites, and long-lived proteins. Deregulation of autophagy results in a variety of pathological conditions, but little is known regarding the mechanisms that link normal cellular and pat...

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Bibliographic Details
Main Authors: Yogalingam, Gouri, Pendergast, Ann Marie
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602914/
https://ncbi.nlm.nih.gov/pubmed/18945674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804543200
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