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Role of ABL Family Kinases in Cancer: from Leukemia to Solid Tumors

The Abelson (ABL) family of nonreceptor tyrosine kinases, ABL1 and ABL2, transduces diverse extracellular signals to protein networks that control proliferation, survival, migration, and invasion. ABL1 was first identified as an oncogene required for the development of leukemias initiated by retrovi...

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Bibliographic Details
Main Authors: Greuber, Emileigh K., Smith-Pearson, Pameeka, Wang, Jun, Pendergast, Ann Marie
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935732/
https://ncbi.nlm.nih.gov/pubmed/23842646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3563
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