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Calcineurin Signaling Regulates Human Islet β-Cell Survival
The calcium-regulated phosphatase calcineurin intersects with both calcium and cAMP-mediated signaling pathways in the pancreatic β-cell. Pharmacologic calcineurin inhibition, necessary to prevent rejection in the setting of organ transplantation, is associated with post-transplant β-cell failure. W...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000987/ https://ncbi.nlm.nih.gov/pubmed/20943662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.154955 |
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