Calcineurin Signaling Regulates Human Islet β-Cell Survival

The calcium-regulated phosphatase calcineurin intersects with both calcium and cAMP-mediated signaling pathways in the pancreatic β-cell. Pharmacologic calcineurin inhibition, necessary to prevent rejection in the setting of organ transplantation, is associated with post-transplant β-cell failure. W...

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Bibliografski detalji
Glavni autori: Soleimanpour, Scott A., Crutchlow, Michael F., Ferrari, Alana M., Raum, Jeffrey C., Groff, David N., Rankin, Matthew M., Liu, Chengyang, De León, Diva D., Naji, Ali, Kushner, Jake A., Stoffers, Doris A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Molecular Bases of Disease
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000987/
https://ncbi.nlm.nih.gov/pubmed/20943662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.154955
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