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Preexisting pancreatic acinar cells contribute to acinar cell, but not islet β cell, regeneration

It has been suggested that pancreatic acinar cells can serve as progenitors for pancreatic islets, a concept with substantial implications for therapeutic efforts to increase insulin-producing β cell mass in patients with diabetes. We report what we believe to be the first in vivo lineage tracing ap...

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Detalhes bibliográficos
Main Authors: Desai, Biva M., Oliver-Krasinski, Jennifer, De Leon, Diva D., Farzad, Cyrus, Hong, Nankang, Leach, Steven D., Stoffers, Doris A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838936/
https://ncbi.nlm.nih.gov/pubmed/17404620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29988
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