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Regulation of Mitochondrial Glutathione Redox Status and Protein Glutathionylation by Respiratory Substrates

Brain and liver mitochondria isolated by a discontinuous Percoll gradient show an oxidized redox environment, which is reflected by low GSH levels and high GSSG levels and significant glutathionylation of mitochondrial proteins as well as by low NAD(P)H/NAD(P) values. The redox potential of brain mi...

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Main Authors: Garcia, Jerome, Han, Derick, Sancheti, Harsh, Yap, Li-Peng, Kaplowitz, Neil, Cadenas, Enrique
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000945/
https://ncbi.nlm.nih.gov/pubmed/20937819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.164160
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