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Regulation of Mitochondrial Glutathione Redox Status and Protein Glutathionylation by Respiratory Substrates

Brain and liver mitochondria isolated by a discontinuous Percoll gradient show an oxidized redox environment, which is reflected by low GSH levels and high GSSG levels and significant glutathionylation of mitochondrial proteins as well as by low NAD(P)H/NAD(P) values. The redox potential of brain mi...

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Detalhes bibliográficos
Main Authors: Garcia, Jerome, Han, Derick, Sancheti, Harsh, Yap, Li-Peng, Kaplowitz, Neil, Cadenas, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000945/
https://ncbi.nlm.nih.gov/pubmed/20937819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.164160
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