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Regulation of Mitochondrial Glutathione Redox Status and Protein Glutathionylation by Respiratory Substrates

Brain and liver mitochondria isolated by a discontinuous Percoll gradient show an oxidized redox environment, which is reflected by low GSH levels and high GSSG levels and significant glutathionylation of mitochondrial proteins as well as by low NAD(P)H/NAD(P) values. The redox potential of brain mi...

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Autors principals: Garcia, Jerome, Han, Derick, Sancheti, Harsh, Yap, Li-Peng, Kaplowitz, Neil, Cadenas, Enrique
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000945/
https://ncbi.nlm.nih.gov/pubmed/20937819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.164160
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