Wordt geladen...
Inhibition of Siah ubiquitin ligase function
Tumor hypoxia induces the up-regulation of Hif-1alpha which in turn induces the expression of genes including VEGF to recruit new blood vessel outgrowth, enabling tumor growth and metastasis. Interference with the Hif-1 pathway and neoangiogenesis is an attractive anti-tumor target. The hydroxylatio...
Bewaard in:
| Hoofdauteurs: | , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000903/ https://ncbi.nlm.nih.gov/pubmed/18850011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.382 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|