Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas

BACKGROUND: Advanced biliary tract carcinomas (BTCs) have poor prognosis and limited therapeutic options. Therefore, it is crucial to combine standard therapies with molecular targeting. In this study EGFR, HER2, and their molecular transducers were analysed in terms of mutations, amplifications and...

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Hlavní autoři: Pignochino, Ymera, Sarotto, Ivana, Peraldo-Neia, Caterina, Penachioni, Junia Y, Cavalloni, Giuliana, Migliardi, Giorgia, Casorzo, Laura, Chiorino, Giovanna, Risio, Mauro, Bardelli, Alberto, Aglietta, Massimo, Leone, Francesco
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000850/
https://ncbi.nlm.nih.gov/pubmed/21087480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-631
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