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Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation

BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is an aggressive, highly lethal tumors and lacks of effective chemo and targeted therapies. Cell lines and animal models, even partially reflecting tumor characteristics, have limits to study ICC biology and drug response. In this work, we created an...

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發表在:BMC Cancer
Main Authors: Cavalloni, Giuliana, Peraldo-Neia, Caterina, Sassi, Francesco, Chiorino, Giovanna, Sarotto, Ivana, Aglietta, Massimo, Leone, Francesco
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750214/
https://ncbi.nlm.nih.gov/pubmed/26868125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2136-1
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