Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation

BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is an aggressive, highly lethal tumors and lacks of effective chemo and targeted therapies. Cell lines and animal models, even partially reflecting tumor characteristics, have limits to study ICC biology and drug response. In this work, we created an...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Cavalloni, Giuliana, Peraldo-Neia, Caterina, Sassi, Francesco, Chiorino, Giovanna, Sarotto, Ivana, Aglietta, Massimo, Leone, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750214/
https://ncbi.nlm.nih.gov/pubmed/26868125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2136-1
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