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Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation
BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is an aggressive, highly lethal tumors and lacks of effective chemo and targeted therapies. Cell lines and animal models, even partially reflecting tumor characteristics, have limits to study ICC biology and drug response. In this work, we created an...
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| Publié dans: | BMC Cancer |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4750214/ https://ncbi.nlm.nih.gov/pubmed/26868125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2136-1 |
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