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Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation

BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is an aggressive, highly lethal tumors and lacks of effective chemo and targeted therapies. Cell lines and animal models, even partially reflecting tumor characteristics, have limits to study ICC biology and drug response. In this work, we created an...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Cavalloni, Giuliana, Peraldo-Neia, Caterina, Sassi, Francesco, Chiorino, Giovanna, Sarotto, Ivana, Aglietta, Massimo, Leone, Francesco
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750214/
https://ncbi.nlm.nih.gov/pubmed/26868125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2136-1
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