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Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation

BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is an aggressive, highly lethal tumors and lacks of effective chemo and targeted therapies. Cell lines and animal models, even partially reflecting tumor characteristics, have limits to study ICC biology and drug response. In this work, we created an...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Cancer
Hauptverfasser: Cavalloni, Giuliana, Peraldo-Neia, Caterina, Sassi, Francesco, Chiorino, Giovanna, Sarotto, Ivana, Aglietta, Massimo, Leone, Francesco
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750214/
https://ncbi.nlm.nih.gov/pubmed/26868125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2136-1
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