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Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation

BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is an aggressive, highly lethal tumors and lacks of effective chemo and targeted therapies. Cell lines and animal models, even partially reflecting tumor characteristics, have limits to study ICC biology and drug response. In this work, we created an...

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Publicado en:BMC Cancer
Autores principales: Cavalloni, Giuliana, Peraldo-Neia, Caterina, Sassi, Francesco, Chiorino, Giovanna, Sarotto, Ivana, Aglietta, Massimo, Leone, Francesco
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750214/
https://ncbi.nlm.nih.gov/pubmed/26868125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2136-1
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