Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas

BACKGROUND: Advanced biliary tract carcinomas (BTCs) have poor prognosis and limited therapeutic options. Therefore, it is crucial to combine standard therapies with molecular targeting. In this study EGFR, HER2, and their molecular transducers were analysed in terms of mutations, amplifications and...

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Autors principals: Pignochino, Ymera, Sarotto, Ivana, Peraldo-Neia, Caterina, Penachioni, Junia Y, Cavalloni, Giuliana, Migliardi, Giorgia, Casorzo, Laura, Chiorino, Giovanna, Risio, Mauro, Bardelli, Alberto, Aglietta, Massimo, Leone, Francesco
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000850/
https://ncbi.nlm.nih.gov/pubmed/21087480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-631
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