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Histone Deacetylase Inhibitors: Advancing Therapeutic Strategies in Hematological and Solid Malignancies

Advancement in the understanding of cancer development in recent years has identified epigenetic abnormalities as a common factor in both tumorigenesis and refractory disease. One such event is the dysregulation of histone deacetylases (HDACs) in both hematological and solid tumors, and has conseque...

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Bibliographic Details
Main Authors: Ellis, Leigh, Pili, Roberto
Format: Artigo
Language:Inglês
Published: MDPI 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000686/
https://ncbi.nlm.nih.gov/pubmed/21151768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3082441
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