Carregant...
Ranolazine selectively blocks persistent current evoked by epilepsy-associated Na(V)1.1 mutations
BACKGROUND AND PURPOSE: Mutations of SCN1A, the gene encoding the pore-forming subunit of the voltage-gated sodium channel Na(V)1.1, have been associated with a spectrum of genetic epilepsies and a familial form of migraine. Several mutant Na(V)1.1 channels exhibit increased persistent current due t...
Guardat en:
| Autors principals: | , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
2010
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000664/ https://ncbi.nlm.nih.gov/pubmed/20735403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00976.x |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|