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Assessing genuine parents-offspring trios for genetic association studies
OBJECTIVES: Family-based association tests such as the transmission disequilibrium test (TDT) are dependent on the successful ascertainment of true nuclear family trios. Relationship misspecification inevitably occurs in a proportion of trios collected for genotyping which undetected can lead to a l...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000594/ https://ncbi.nlm.nih.gov/pubmed/18931507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000164396 |
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