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Assessing genuine parents-offspring trios for genetic association studies
OBJECTIVES: Family-based association tests such as the transmission disequilibrium test (TDT) are dependent on the successful ascertainment of true nuclear family trios. Relationship misspecification inevitably occurs in a proportion of trios collected for genotyping which undetected can lead to a l...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000594/ https://ncbi.nlm.nih.gov/pubmed/18931507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000164396 |
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