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Power consequences of linkage disequilibrium variation between populations

We quantify the degree to which LD differences exist in the human genome and investigates the consequences that variations in patterns of LD between populations can have on the power of case-control or family-trio association studies. Although only a small proportion of SNPs show significant LD diff...

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Autors principals: Teo, Yik Y., Small, Kerrin S., Fry, Andrew E., Wu, Yumeng, Kwiatkowski, Dominic P., Clark, Taane G.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997478/
https://ncbi.nlm.nih.gov/pubmed/18814308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20366
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