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Power consequences of linkage disequilibrium variation between populations

We quantify the degree to which LD differences exist in the human genome and investigates the consequences that variations in patterns of LD between populations can have on the power of case-control or family-trio association studies. Although only a small proportion of SNPs show significant LD diff...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Teo, Yik Y., Small, Kerrin S., Fry, Andrew E., Wu, Yumeng, Kwiatkowski, Dominic P., Clark, Taane G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997478/
https://ncbi.nlm.nih.gov/pubmed/18814308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20366
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