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Interaction of Salicylate and a Terpenoid Plant Extract with Model Membranes: Reconciling Experiments and Simulations

We investigate the effects of two structurally similar small cyclic molecules: salicylic acid and perillic acid on a zwitterionic model lipid bilayer, and show that both molecules might have biological activity related to membrane thinning. Salicylic acid is a nonsteroidal antiinflammatory drug, som...

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Detalhes bibliográficos
Main Authors: Khandelia, Himanshu, Witzke, Sarah, Mouritsen, Ole G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000517/
https://ncbi.nlm.nih.gov/pubmed/21156130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.009
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