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Lipid Gymnastics: Evidence of Complete Acyl Chain Reversal in Oxidized Phospholipids from Molecular Simulations

In oxidative environments, biomembranes contain oxidized lipids with short, polar acyl chains. Two stable lipid oxidation products are PoxnoPC and PazePC. PoxnoPC has a carbonyl group, and PazePC has an anionic carboxyl group pendant at the end of the short, oxidized acyl chain. We have used MD simu...

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Autors principals: Khandelia, Himanshu, Mouritsen, Ole G.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711301/
https://ncbi.nlm.nih.gov/pubmed/19348756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.007
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