Increased expression of leukotriene C(4) synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm

Leukotrienes (LTs) are arachidonic acid-derived lipid mediators involved in the pathogenesis and progression of diverse inflammatory disorders. The cysteinyl-leukotrienes LTC(4), LTD(4), and LTE(4) are important mediators of asthma, and LTB(4) has recently been implicated in atherosclerosis. Here we...

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Hauptverfasser: Di Gennaro, Antonio, Wågsäter, Dick, Mäyränpää, Mikko I., Gabrielsen, Anders, Swedenborg, Jesper, Hamsten, Anders, Samuelsson, Bengt, Eriksson, Per, Haeggström, Jesper Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000261/
https://ncbi.nlm.nih.gov/pubmed/21078989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015166107
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