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Differential correction of lagging-strand replication errors made by DNA polymerases α and δ

Mismatch repair (MMR) of replication errors requires DNA ends that can direct repair to the newly synthesized strand containing the error. For all but those organisms that use adenine methylation to generate nicks, the source of these ends in vivo is unknown. One possibility is that MMR may have a “...

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Main Authors: Nick McElhinny, Stephanie A., Kissling, Grace E., Kunkel, Thomas A.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000245/
https://ncbi.nlm.nih.gov/pubmed/21041657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013048107
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