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Molecular etiology of a dominant form of type III hyperlipoproteinemia caused by R142C substitution in apoE4
We have used adenovirus-mediated gene transfer in apolipoprotein (apo)E(−/−) mice to elucidate the molecular etiology of a dominant form of type III hyperlipoproteinemia (HLP) caused by the R142C substitution in apoE4. It was found that low doses of adenovirus expressing apoE4 cleared cholesterol, w...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999928/ https://ncbi.nlm.nih.gov/pubmed/20861163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M008409 |
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