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Multiple Pharmacophores for the Selective Activation of Nicotinic α7-Type Acetylcholine Receptors
The activation of heteromeric and homomeric nicotinic acetylcholine receptors was studied in Xenopus laevis oocytes to identify key structures of putative agonist molecules associated with the selective activation of homomeric α7 receptors. We observed that selectivity between α7 and α4β2 was more r...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999882/ https://ncbi.nlm.nih.gov/pubmed/18768388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.048892 |
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