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Maternally transferred anti-factor VIII IgG reduce the anti-factor VIII humoral immune response in factor VIII-deficient mice

Replacement therapy with exogenous factor VIII (FVIII) to treat haemorrhages or used in prophylaxis induces inhibitory anti-FVIII immunoglobulin G (IgG) in some patients with haemophilia A. Therapeutic strategies to prevent the onset of the deleterious anti-FVIII immune response are still lacking. M...

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Bibliografski detalji
Glavni autori: Meslier, Yann, André, Sébastien, Teyssandier, Maud, Kaveri, Srinivas V, Lacroix-Desmazes, Sébastien
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999805/
https://ncbi.nlm.nih.gov/pubmed/20673239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03327.x
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