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A Differential Drug Screen for Compounds That Select Against Antibiotic Resistance

Antibiotics increase the frequency of resistant bacteria by providing them a competitive advantage over sensitive strains. Here, we develop a versatile assay for differential chemical inhibition of competing microbial strains, and use it to identify compounds that preferentially inhibit tetracycline...

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Detalhes bibliográficos
Main Authors: Chait, Remy, Shrestha, Shreya, Shah, Aakash Kaushik, Michel, Jean-Baptiste, Kishony, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999542/
https://ncbi.nlm.nih.gov/pubmed/21209699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015179
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