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Predicting siRNA potency with random forests and support vector machines

BACKGROUND: Short interfering RNAs (siRNAs) can be used to knockdown gene expression in functional genomics. For a target gene of interest, many siRNA molecules may be designed, whereas their efficiency of expression inhibition often varies. RESULTS: To facilitate gene functional studies, we have de...

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Detalhes bibliográficos
Main Authors: Wang, Liangjiang, Huang, Caiyan, Yang, Jack Y
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999347/
https://ncbi.nlm.nih.gov/pubmed/21143784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-S3-S2
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