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Predicting siRNA potency with random forests and support vector machines
BACKGROUND: Short interfering RNAs (siRNAs) can be used to knockdown gene expression in functional genomics. For a target gene of interest, many siRNA molecules may be designed, whereas their efficiency of expression inhibition often varies. RESULTS: To facilitate gene functional studies, we have de...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999347/ https://ncbi.nlm.nih.gov/pubmed/21143784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-S3-S2 |
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