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Modulation of drug block of the cardiac potassium channel KCNA5 by the drug transporters OCTN1 and MDR1
BACKGROUND AND PURPOSE: A common site for drug binding on voltage-gated ion channels is at the interior face of the channel pore. In this study, we tested the hypothesis that the extent of drug block of the human cardiac KCNA5 (K(v)1.5) channel underlying the atrial-specific, ultra-rapidly activatin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998684/ https://ncbi.nlm.nih.gov/pubmed/20977453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00932.x |
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